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Absorption problems Even with adequate intake, absorption can be reduced by: Certain gastrointestinal conditions affecting the stomach or small intestine Some medications Age-related reduction in stomach acid (which can affect absorption) Autoimmune gastritis (often historically referred to as pernicious anaemia) This is a well-recognised cause of B12 deficiency and may require ongoing management

Assuming a 1:1:1 group allocation ratio, a sample size of 29 teeth per group was required to achieve 80% power to detect between-group differences

A 12-week study of NMN supplements showed better vascular health

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