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4%17% in placebo) [98]

dTBI caused dose dependent and long-lasting neurological deficits, including deficits in righting reflex, climbing, and diminished life span
At any given pH of the bulk of the solution, the pH of the diffusion layer (saturation solubility of the drug) of the salt form of a weak acid will be higher than that observable with the free acid form of the drug (can be practically observed in the laboratory)

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Edden, R
