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The interplay of NAD + /NADP + metabolism with circadian clock is further evidenced by the oscillating redox, in which ROS levels display a different liver pattern compared to other tissues due to the unique NAD + oscillation in response to the autonomous hepatic clock

Each named in research-context only (e.g., "studied in research models")

The intended context of use of our system is to support individualized DILI risk prediction rather than broad preclinical screening across large drug libraries

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