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Clinical uses Aphthous ulcers Aphthous (mouth) ulcers are common lesions in the oral mucosa, affecting up to 50% of the general population

Retrieved May 27, 2025, from [ \- Link Opens in New Tab]( National Library of Medicine

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Loss of NAD homeostasis leads to progressive and reversible degeneration of skeletal muscle

This is because folate supplementation may improve symptoms to the point that the B12 deficiency is not detected in tests, and therefore is not treated