hepatic glutathione antioxidant defense system The Biological Functions of Glutathione - an overview |

This could be detrimental since it would disable the flux of metabolites through the Krebs cycle

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In humans, VitE insufficiency is linked to cystic fibrosis, ataxia, and abetalipoproteinemia (a condition that interferes with the proper absorption of fat and fat-soluble vitamins from meals), while in experimental animals, it is linked to frequent abortions and testicular degeneration

TFDP1 heterodimerizes with E2F proteins to enhance their DNA-binding activity and promote transcription from E2F target genes 57