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These experiments essentially exclude a metabolic role for extrahepatic FX synthesis in the activation of PAR2 outside of the vascular system but delineate an important regulatory role of FXa-PAR2 signaling in controlling ATM activation and adipose tissue inflammation

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Vitamins E, A and B2 as possible risk factors for preeclampsia under consideration of the PROPER study (prevention of preeclampsia by high-dose riboflavin supplementation)
