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O., Southard J
For 21 days, ketamine (50 mg/kg, i.p.) administration significantly produced increased locomotor activity and stereotypic behaviors (positive symptoms), increased immobility duration (negative symptoms) and cognitive deficits (increases transfer latency) weakens oxidative defense and mitochondrial function
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Studies show that the concentration may fall from 200 ng/mL at 20 years old to just 80 ng/mL at 60 years of age
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