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Abstract Introduction: The development of organotypic slice cultures of central nervous system (CNS) tissues has bridged the gap between simple in vitro cell cultures and complex in vivo whole animal studies

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The real question for cagrilintide isnt whether it beats tirzepatide solo, but whether its mechanism earns it a complementary role: either as part of a combination like CagriSema or as a standalone option for people who need something outside the GLP-1 family

Though human studies are lacking, preclinical trials support its potential in treating fractures

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