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Complementary clinical and meta-analytic data consistently demonstrate systemic redox imbalance, including lower glutathione reserves, altered GSH/GSSG ratios, increased lipid peroxidation, and dysregulated NRF2 signaling, linking oxidative status to immune activation and synaptic dysfunction (James et al., 2004

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95 Similarities between the processes of bone loss and the buildup of calcium along the artery walls (arterial or vascular calcification) are striking

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Subjects averaged 44.4 years of age, with a range of 17 to 95 years, and the majority of patients were female and white