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Leptin Induces Oxidative Stress Through Activation of NADPH Oxidase in Renal Tubular Cells: Antioxidant Effect of L-Carnitine

Milella M, Kornblau SM, Estrov Z, Carter BZ, Lapillonne H, Harris D, Konopleva M, Zhao S, Estey E, Andreeff M

ROS inhibits cancer cell invasion and migration by regulating the key JAK2/STAT3 signaling pathway

Examples of such functions include reducing oxidative stress, increasing expression of pro-inflammatory cytokines (24), and improving mitochondrial dysfunction (5) and insulin resistance (IR) (6, 7)
