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The multiple phosphate-binding interactions to a common surface along NBD1 and the Lasso motif explain the well-known robustness to loss of any single phosphorylation site on the R-domain 9,11 and the requirement for an intact N-terminus containing the Lasso motif of CFTR for activity 33
Avoid combining with other NSAIDs or heavy alcohol use
Neurosci Lett 590:2934 Gjurasin M, Miklic P, Zupancic P et al (2010) Peptide therapy with pentadecapeptide BPC 157 in traumatic nerve injury
Harnessing natures arsenal: targeting the tgf-/smad cascade with novel natural anti-fibrotic agents
