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[DOI] [PMC free article] [PubMed] [Google Scholar] 152.Chen K, Gong W, Huang J, Yoshimura T, Wang JM
R001 strongly inhibits growth of subcutaneous human breast cancer xenografts in mice associated with reduced levels of G6PD and Trx1 and phospho-tyr STAT3 We determined the antitumor effects of R001
The downregulation of PHB1 by HDAC6 interfered with the mitochondrial respiratory chain, resulting in increased oxidant production and oxidative stress, leading to severe oxidative damage in multiple organs (81)
5B), respectively
PMID: 36332375 J Food Process Preserv26 July 2022
