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Melanocytes are cells that make pigment, which is incorporated into the hair shaft, giving hair its distinctive color. When these melanocytes start to reduce and their count is not replenished, the pigment in the hair shaft is also reduced, eventually causing the hair to turn white

Moderate-to-severe psoriasis often requires systemic treatment

Shi Y, Wang Y, Shao C, Huang J, Gan J, Huang X, et al

Moreover, diverse extracellular molecular signals, including neurotransmitters, neurotrophins, extracellular matrix proteins, contact-mediated ligands, and secreted diffusible cues, shape neural circuit development and modulate brain connectivity during early life ( There is increasing recognition that imbalances in the gut microbial community, referred to as dysbiosis, are associated with a range of neurological disorders

Mastrocola RRestivo F, Vercellinatto I, Danni O, Brignardello E, Aragno M, Boccuzzi G