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AOD9604 has been characterised across pre-clinical, safety pharmacology, and early-phase clinical research since the late 1990s, with peer-reviewed publications spanning lipid metabolism, adipose biology, joint repair, and bioavailability

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Animal studies indicate that paeoniflorin administration can ameliorate PD-like motor deficits and prevent the loss of dopaminergic neurons in both MPTP mouse and 6-OHDA rat models (35, 36)

For example, increased oxidative damage to guanine in Parkinsons disease or to specific proteins in Alzheimers disease suggests a high degree of specificity (Halliwell, 2006

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