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In particularly, ACSL4 plays a crucial role in regulating ferroptosis, and its overexpression boosts the synthesis of -pufa6 PUFA and encourages ferroptosis (51)

4.1.2.2 Microglia targeted lipid nanoparticles Lipid nanoparticles (LNPs) functionalized with targeting ligands ( e.g

It also modulates nitric oxide pathways, helping regulate inflammation and blood flow