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Acknowledgements This work was supported by the National Natural Science Foundation of China [grant number 62376256], Research Funds of Centre for Leading Medicine and Advanced Technologies of IHM [grant number 2023IHM01041], Clinical medical research Transformation Project of Anhui Province [Grant Number 202204295107020020], and the Joint Fund for Medical Artificial Intelligence [Grant number MAI2022Q011]

Withanolides have been reported to regulate the inflammatory pathways such as NF-B, JAK/STAT, Nrf2, and HIF-1

Nonetheless, it is crucial to acknowledge that these mechanisms remain conjectural and warrant further empirical investigation to be substantiated

doi: 10.1016/j.jconrel.2022.03.017 [DOI] [PubMed] [Google Scholar] 64.Barros C, Aranha N, Severino P, et al

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