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In our experimental design, we established a D-galactose-induced aging mouse model and injected the experimental group mice with FOXO4-DRI for 1 month, while the control group was injected with equal amounts of PBS

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The most detrimental clinical presentation is fulminant liver failure, where patients without a history of liver disease present with hepatic encephalopathy and coagulopathy preceding jaundice

The particle population for each dataset was further enriched by three-dimensional (3D) classification to remove broken and overlapping particles
