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A Vit B12 deficiency can result in neurological symptoms, such as: Mental Health Issues : Deficiency of B12 has also been found to cause depression, anxiety and fluctuating moods

And no, spirulina, mushrooms, or fermented foods are not reliable B12 sources despite what social media keeps repeating

People who have MTHFR People with MTHFR mutations are advised to supplement with active forms of B12 to support proper methylation

4.2.2 NAM-competitive inhibitors NAM-competitive inhibitors are substances that can compete with the substrate NAM for the binding site in NNMT

Contraindications Severe and acute forms of decompensated heart failure Pregnancy Lactation (thoracicreinforcement) Hypersensitivity to the drug