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Tracking the engraftment and regenerative capabilities of transplanted lung stem cells using fluorescent nanodiamonds

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These amalgams are traditionally made of a mix of mercury and a metal alloy that contains copper, silver or tin, which are used to fill dental cavities

It is important to acknowledge that this thio-disulfide exchange based protein oligomerization inducer may face several challenges: (i) so far, it has only been tested on WDR5, and further exploration is needed to determine its applicability to other proteins, (ii) the disulfide bonds induced by WZ-1 are susceptible to cleavage under strong reducing conditions, so we need to develop strategies to ensure stable linkages that remain unaffected by intracellular environments, (iii) challenges persist in translating oligomerization inducers into viable drugs, primarily stemming from unforeseen oligomerization scenarios, such as excessive oligomerization and off-target proteins interactions