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Description
One cycle starts with a component known as 10-formylTHF which is associated with purine production and two cycles utilize 5, 10-methyleneTHF in deoxythymidine monophosphate (dTMP) and methionine production
PubMed, Locksley, Richard M., et al
DNA methylation reader MECP2: cell type- and differentiation stage-specific protein distribution
This may mean slower titration and lower overall doses to avoid overstimulating the system
doi: 10.1161/CIRCRESAHA.108.176867
