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For example, the senescence of cardiac endothelial cells may exacerbate myocardial ischemia and heart failure

In animal models, the development of atherosclerotic lesions has been reported to be inhibited by lutein supplementation [5658]

To gain insight into the mechanism of action of HSP90 inhibition, we conducted a co-immunoprecipitation analysis from the 293T cells expressing FLAG-RAD23B

The active factor turned out to be a tiny tripeptide: glycyl-L-histidyl-L-lysine, bound to a copper ion

Also, in this work, the authors observed that in cortical neurons treated with 6-hydroxydopamine, paeonol attenuated the production of ROS, increased the activity of SOD1 and the expression of the antiapoptotic protein B-cell lymphoma 2 [181]