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Mast cell activation syndrome, or MCAS, is an immunological condition where the mast cells in the body release excessive amounts of chemical mediators such as histamine, leading to symptoms such as hives, flushing, rashes, swelling, low blood pressure, dizziness, brain fog, breathing difficulties, and even anaphylaxis. I have found that mast cell disorders can impact []

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With advances in next generation sequencing technologies, more disorders related to ISC biogenesis defects are expected to be elucidated