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In particular, Akt phosphorylation, compared to ERK phosphorylation, appeared to be more sensitive to the phosphorylation of Met, which is evident by the dramatic reduction in pAkt in the case without 51 (Fig
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This staged approach maximizes both tissue loading and active utilization
Kidney Blood Press
The proposed reason the combination is more than the sum of its parts is that amylin agonism appears to sensitize hypothalamic leptin signaling
