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This pathway controls tendon fibroblast migration and survival, directly influencing the cellular repair process

This dose also demonstrated cardiovascular risk reduction in the SELECT trial

2021;372(6547):1224 to 1229

Mechanistic Comparison# Dosing Comparison# Amycretin Dosing# Amycretin dosing is investigational: Subcutaneous: Once-weekly injection, doses up to 60 mg studied in phase 1b/2a over 36 weeks Oral: Daily tablet, doses up to 50 mg (or 2 x 50 mg) studied in phase 1 Phase 2 T2D: Both subcutaneous and oral formulations studied over 36 weeks Phase 3 dose selection will be informed by the completed phase 2 data

It detects light and controls the circadian rhythm of the body