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Given this situation it is particularly concerning that MDA campaigns show that PZQ cure rates are often less than 50% and modeling studies demonstrating that these campaigns with PZQ alone are unlikely to interrupt transmission, and once MDA is suspended, the prevalence of infection is likely to rebound to pre-MDA levels 9,10,11
Dosing tiers: Administer two to three hours before intended sleep time, not immediately at bedtime
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