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Interestingly, the nuclear GSH pool appears to be dynamic and independent of cytosolic GSH, undergoing major shifts in relative concentration throughout the cell cycle which reaches upwards of four times the concentration found in the cytosol [76]
Knocked down PINK1 in SHSY5Y cells results in inhibition of mDNA synthesis, disruption of key indicators of mitochondrial activity, mitochondrial membrane potential, and suppressed production of ATP (Gegg et al
Angiogenesis plays an important role in tumorigenesis, tumor invasion and metastasis, and inhibiting angiogenesis represents a therapeutic direction for cancers
Potential benefits of the self-administration of subcutaneous methotrexate with autoinjector devices for patients: A Review
141 It is critical for maintaining protein homeostasis (proteostasis)
