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Hypokalaemia (low blood potassium) in the first weeks of loading-dose treatment in patients who started severely deficient

Blocks NNMT in fat cells In 3T3-L1 mouse fat cells, 30 M of 5-Amino-1MQ for 24 hours strongly lowered 1-MNA levels direct proof of NNMT inhibition (Neelakantan et al., Biochemical Pharmacology, 2018)

Recognising the link between tiredness and vitamin B12 deficiency is crucial, as early diagnosis and treatment can prevent serious, potentially irreversible neurological complications whilst restoring energy levels and overall wellbeing

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