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demonstrated that IgE-activated mast cells can drive macrophage polarization, phagocytosis, and antibacterial activity by influencing metabolic and epigenetic processes in macrophages ( 2.3 Myeloid-derived suppressor cells Myeloid-derived suppressor cells (MDSCs) comprise pathologically activated neutrophils and monocytes that exhibit potent immunosuppressive activity ( 2.4 Dendritic cells Dendritic cells are professional antigen-presenting cells that link the innate to the adaptive immune system

Further exposure of the Parkinsonian flies to Sp resulted in diseased flies to display more number of viable non-stressed dopaminergic neurons than the non-treated ones