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Following the renaissance and promotion of TCM, mounting studies currently spotlight the seminal applications of herbs in the prevention and treatment of skeletal lesions and envisage their potential mechanisms via the gutbone axis

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Nutrients 10, 1494

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The latter then donates an amino group to an alpha-keto acid, alpha-ketoglutarate, to form an amino acidpyridoxal 5-phosphate Schiffs base intermediate that is then reduced to form glutamate

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