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Nevertheless, according to magnetic resonance physics, at least a fraction of the GBCA-contrast information due to blood vessels is present and partially encoded, in non-contrast structural MRI scans through a non-linear function

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We can apply heuristic approximations and simple metrics at a general average level, but the final answer will be determined by each person's physiology

Important caveat: Ara-290 has been evaluated only through Phase 2/2b trials
