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Description
The method is designed to raise the circulating blood levels of glutathione via the administration of an effective amount of SAG in a delayed release composition

Inhibition of mitochondrial translation, mitochondrial chaperonin, CLPB or even mitophagy regulator, FIS1 (Mitochondrial Fission 1 protein) and its upstream target AMPK leads to loss of LSC self-renewal potential, myeloid differentiation, and cell cycle arrest and ultimately cell death even for the resistant AML LSCs (2628)
This alteration may extend the peptide's half-life by mitigating enzymatic cleavage
doi: 10.1002/cyto.990030114
Lv Y, Liang C, Sun Q, Zhu J, Xu H, Li X, et al