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It acts as a cushion between the two bones and prevents fluid, called synovial fluid, from escaping from the joint

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This selectivity represents a fundamental difference from not only full-length growth hormone but also growth hormone secretagogues and analogs like tesamorelin, which increase endogenous growth hormone and subsequently elevate IGF-1

et al.: Low vitamin B-12 status in confirmed Alzheimers disease as revealed by serum holotranscobalamin (2003) Journal of neurology, neurosurgery, and psychiatry | DOI: 10.1136/jnnp.74.7.959