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Bloodbrain barrier and BCB are guarding systems of the brain formed mainly by endothelial cells, which separate the central nervous system (CNS) from the general circulatory system of the body, protecting the brain from toxic metabolites and pathogens (Zenaro et al., 2017)

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Human skin retention and penetration of a copper tripeptide in vitro as function of skin layer towards anti-inflammatory therapy

This suggests that structural differences may give rise to localized activity