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In PD, mutations in GBA, ATP13A2, and PARK9 impair lysosomal function, leading to -synuclein accumulation and cellular toxicity (Behl et al., 2022
Karmali PP, et al
Understand the role of radiolabelled peptides and molecular imaging in enhancing the precision of disease monitoring
It senses the accumulation of misfolded proteins in the ER and activates its ribonuclease activity to splice XBP1 mRNA, producing the active spliced form of XBP1 (XBP1s)
Sodhi M, Rezaeianzadeh R, Kezouh A, Etminan M
