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Caspase-3 activation is an early event and initiates apoptotic damage in a human leukemia cell line

conducted a randomized, double-blind, placebo-controlled trial involving 150 patients who underwent selective large hepatectomy and determined that perioperative terlipressin did not affect the endpoint of liver-specific complications, but did significantly prevent postoperative liver function degradation

Upon inhalation, PAHs are bioactivated by cytochrome P450 (CYP450) enzymes, converting them into highly reactive electrophiles such as diol-epoxides and redox-active quinones

Tox Appl Pharmacol