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To determine whether induced expression of IRF5 and IKK effectively reprogrammed macrophages from M2 to M1, researchers generated M2 macrophages by culturing bone marrow-derived macrophages (BMDMs) with IL-4

Lip 2 , Ching Hui Sia 1 , Benjamin Tan 1 1 National University of Singapore, Singapore, Singapore, 2 University of Liverpool, Liverpool, United Kingdom Background and Aims: The differential impact of atrial fibrillation detected after stroke (AFDAS) compared to known atrial fibrillation (kAF) on outcomes following thrombolysis with intravenous recombinant tissue plasminogen activator (rtPA) in ischemic stroke patients remains unclear.We aimed to evaluate the effect of AF status no AF, kAF, or AFDAS on functional and survival outcomes in ischemic stroke patients treated with thrombolysis

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10.1038/srep28833 38 YanT.JiangX.LinG.TangD.ZhangJ.GuoX.et al (2019)