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In response to a classical activation signal such as lipopolysaccharide, the polarization of naive macrophages into a pro-inflammatory state requires coupled metabolic remodelling 92,93
[61] suggested TMAO as a pro-atherogenic factor
[DOI] [PMC free article] [PubMed] [Google Scholar] 171.Blanchard JW, et al
In recent years, non-pharmacological treatments such as physical therapy, exercise therapy, cell therapy, and nanoparticles have shown great potential in mitigating disease progression and alleviating clinical symptoms
However, LDX acts on more targets than MPH
