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The mechanism involved in riboflavin uptake by colonocytes has been characterized and involves an efficient and specific carriermediated mechanism that is similar to the one described in the small intestine (36, 37)

Therefore, in most cases, the variation of 2,3-DPG levels is often a consequence rather than a cause

locus coeruleus J Neurochem
Metalloproteinases and Their Tissue Inhibitors in Alzheimer's Disease and Other Neurodegenerative Disorders. Cellular and Molecular Life Sciences 76: 31673191
Advances in understanding the function of alpha-synuclein: implications for Parkinson's disease