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Nat Rev Neurosci 12: 284296, 2011

and Cerniglia, C.E

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Inhibition of either the Notch or Wnt pathway at early cochlear development results in diminished prosensory regions and prevented hair cell differentiation, suggesting that the pathways may intersect at least at this developmental stage (Brooker et al., 2006)

While the total number of reticulocytes increased by almost 3-fold and the ratio of reticulocytes to total proerythroblasts increased from 140 in wt mice to 240 in mice with Gpx4 -deficient hematopoiesis, RBC counts decreased to 65% (Figure 3L-M) indicating that maturation of reticulocytes to erythrocytes is defective under Gpx4 -deficiency