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1 H NMR (400 MHz, DMSO- d 6 ) 12.31 (s, 1H), 11.13 (s, 1H), 7.88 (d, J = 8.2 Hz, 1H), 7.847.76 (m, 1H), 7.64 (d, J = 7.1 Hz, 1H), 7.40 (s, 1H), 6.73 (d, J = 4.9 Hz, 1H), 5.12 (dd, J = 12.8, 5.4 Hz, 1H), 4.41 (d, J = 12.7 Hz, 1H), 4.06 (s, 2H), 3.91 (d, J = 12.9 Hz, 1H), 3.193.13 (m, 2H), 3.05 (t, J = 11.8 Hz, 1H), 2.89 (td, J = 13.5, 6.4 Hz, 1H), 2.74 (t, J = 11.2 Hz, 1H), 2.682.52 (m, 5H), 2.112.02 (m, 1H), 1.921.77 (m, 4H), 1.631.51 (m, 1H), 1.481.37 (m, 1H), 1.18 (s, 9H)

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6 In the fifties, when chemotherapy wasnt available yet, children with neuroblastoma (a tumour of the autonomous nervous-system) received 1 mg B12 injections every other day during 2 to 3 years in a London childrens hospital

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