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It is thought to affect some 17 to 24 million people worldwide (8) and the United States (U.S.) Centres for Disease Control and Prevention (CDC) and the U.S
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Novel strategies for PI3K/AKT/mTOR pathways The activation of the phosphoinositide 3-kinase (PI3K)/protein kinase B (AKT)/mammalian target of rapamycin (mTOR) pathway plays a crucial role in endocrine resistance, positioning this pathway as a potential therapeutic target
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