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Under pathological conditions, microgliaas a function of different stimuliare activated to exert neuroprotective effects (M2 phenotype) or to release inflammatory factors and neurotoxic substances (M1 phenotype)

PMID: 32720683 Chang M, Russo GS, Canseco JA, Nicholson K, Sharma R, Koomson J, Vaccaro A.R

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Compare with similar compounds BPC-157 and TB-500 are the two most-studied tissue-repair peptides and are often examined together see the BPC-157 + TB-500 blend for combined-compound research convenience

Specific mechanisms may involve oxidative damage caused by excessive ROS production, and the persistent accumulation of such damage can lead to further cellular and organismal dysfunction, ultimately inducing various diseases [34]