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It is used as a chemical probe to study ERR-dependent regulation of oxidative metabolism in cells and animal models

The adoption of large-scale collaborative research, standardization of definitions and analyses, pilot examination of interventions, and improvement in study design standards, peer review, reporting, and dissemination of research have been identified as crucial actions to enhance the validity of scientific works (302)

The mechanisms that regulate the nucleo-cytoplasmic shuttling are, therefore, of extreme importance

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