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In WT mice, although cagrilintide treatment led to significant weight loss, the changes in body composition compared to vehicle-treated mice did not reach statistical significance, with fat mass decreasing by 7% ( P = 0.2) and lean mass increasing by 5% ( P = 0.14

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doi:10.1016/S0140-6736(23)01053-X Sanyal AJ, Kaplan LM, Frias JP, et al