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The pGO-Pt/DOX induced the most prominent cancer cell apoptosis and necrosis rate with 18.6%, which was observed almost 2 times higher than that of pGO-Pt or pGO-DOX groups

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Therapeutic avenues under investigation include anti-inflammatory and metabolic modulators, senolytics, hormone/secretagogue approaches, and regenerative platforms leveraging stem cells, lacrimal organoids, and bioengineered scaffolds
