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For very high disease activity, you may even go right to an IL-17 blocker and bypass anti-TNFs, which have not proven as effective for ankylosing spondylitis as they have been for other types of inflammatory arthritis
After 24 h, treated biofilm supernatant was washed once with 1 PBS followed by addition of 200 L of 1 PBS plus 15 L resazurin 0.05% w/v solution, and incubated for a further 24 h, at 37C, 150 rpm
PNPLA3, patatin-like phospholipase 3
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