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Mohamed Hussein AAR, Galal I, Amin MT, Moshnib AA, Makhlouf NA, Makhlouf HA, et al

Although pediatric cases of T-ALL have a cure rate exceeding 80% with current intensified chemotherapies, the outcome of T-ALL patients with primary resistant or relapsed leukemia remains extremely poor (Winter et al., 2015)

In human ovarian carcinoma cells, CXCR2 activation induced angiogenesis through enhanced expression of VEGF and knockdown reduced tumorigenesis in nude mice [196]

It involves the conversion of acetyl-CoA to ketone bodies: AcAc, BHB, and acetone

Moreover, because of down-regulating the expression of CXCR4 in B cells, B cell motility was reduced which potentially resulted in the expulsion of B cells from BM