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Upregulation of reactive oxygen species (ROS) levels is a principal feature observed in the brains of neurodegenerative diseases such as Parkinsons disease (PD) and Alzheimers disease (AD)

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Co-administration of valproate (400 mg t.i.d.) with phenytoin (250 mg) in normal volunteers (n=7) was associated with a 60% increase in the free fraction of phenytoin

Last October, a 42 year old project manager named Daniel in Austin told me something I've heard dozens of times now: "I wasn't expecting to feel the...
