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The Asp200 carboxylate stabilizes the positive charge of the histidine after proton abstraction from the C1 hydroxyl of G6P, allowing transfer of the C1 hydride to the nicotinamide ring of the coenzyme (Fig

10.1111/j.1365-313X.2008.03761.x Plant J

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With some strains of inbred mice, the manifestations may mimic those seen in human Lyme disease (e.g
