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Obesity (Silver Spring) 2009;17(3 ): 494503

What Most People Get Wrong About B12 Injections and Weight Loss Most people assume B12 injections work like a metabolism switch inject it, burn more calories

The same paper examines a few treatments

Up to 60% of people have a version of this mutation leading to a decreased ability to absorb B12

3 Extended Administration Pharmacokinetics in DIO Mice Neelakantan et al., Biochemical Pharmacology (2024) This study reported a 28-day once-daily administration protocol of 5-Amino-1MQ in diet-induced obese mice, characterizing plasma pharmacokinetics, tissue distribution, and effects on body composition, fatty liver pathology, and circulating biomarkers